A useful antidote to legal complacency

Translational Antidote Research: A Bedside to Bench Tale

Although antidote development should proceed in an orderly fashion from observation, to experimental and safety studies, to clinical trials, this sequence is not always precisely followed. The development of fomepizole as an antidote for toxic alcohol and glycol poisoning is an example of how this may not be the case. Interest in the development of fomepizole was spurred in the 1960s. Shortly t...

Complacency--the silent killer.

Complacency in coronary care.

From modest beginnings in 1962 in Kansas City, Philadelphia, and Toronto, the coronary care unit has become at once an institution and a revolution in the treatment of acute myocardial infarction. The CCU was synthesized from now well known innovations in resuscitation, monitoring, and in the electrical treatment of arrhythmias. Its early history was written by small units of three to four beds...

Belladona an Antidote to Opium

grains viij of solid opium, but he did not weigh it. At midnight it was discovered that he was sleeping so soundly that he could not be awaked. Dr. C. M. Smith saw him three-quarters of an hour later, viz., at a quarter to one on the morning of the 19th. lie was then perfectly insensible, his pupils were contracted to the size of a pin's head, and his breathing sterterous. Dr. Smith gave him an...

Student authority: Antidote to alienation

The widespread disaffection of students from school is manifested in academic failure, indifference, and defiance. These problems can be alleviated, I argue, when an authority structure is developed that combines three components – freedom, power, and legitimacy. Authority understood as either power or freedom is apt to subvert students’ school attachment even while attempting to strengthen it;...